Prepare the pork: Pat tenderloin dry and season generously with salt and pepper. Place in your crockpot.
Make the glaze base: In a bowl, whisk together brown sugar, balsamic vinegar, soy sauce, garlic, and honey. Pour over the pork.
Cook: Cover and cook on low for 4–5 hours, or until tender and easily shredded with a fork.
Make the glaze: Transfer pork to a plate and cover with foil. Pour the liquid from the crockpot into a saucepan. Whisk cornstarch and water together, then stir into the sauce. Simmer until thick and glossy.
Serve: Slice pork into medallions, drizzle glaze over top, and serve warm with your favorite sides.
Notes
Refrigerate leftovers up to 4 days or freeze up to 2 months. Reheat gently with a splash of water or broth to keep it juicy.